Can you take niacin with fenofibrate?

Can you take niacin with fenofibrate?

No interactions were found between fenofibrate and niacin.

Can you take niacin with rosuvastatin?

Using rosuvastatin together with niacin may increase the risk of a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue. In some cases, rhabdomyolysis can cause kidney damage and even death. The risk is greatest if you are elderly or have preexisting kidney disease.

Can you take niacin with pravastatin?

Talk to your doctor before using niacin and pravastatin. This combination may cause unexplained muscle pain, tenderness, or weakness, particularly if accompanied by chills or fever. If you take both medications together, tell your doctor if you have any of these symptoms.

Can you use statin and fibrate together?

Short-term clinical studies have shown that combined therapy with statin and fenofibrate is more effective in controlling atherogenic dyslipidemia in patients with T2DM, the MS or combined dyslipidemia than the administration of either drug alone [18,55,56,57,58•].

Are there any drug interactions between statins and fibrates?

Possible Drug Interactions. Fibrates may increase the risk of experiencing statin side effects. Sandimmune or Neoral (cyclosporine) may increase the number of statins present in the blood and may also increase side effects. Fluvoxamine may increase the concentration of some statins present in the blood and may also increase statin side effects.

Is it safe to take niacin with a statin?

The US Food and Drug Administration (FDA) is withdrawing the indication of extended-release niacin and delayed-release fenofibrate when used in combination with a statin following disappointing clinical trials that showed no evidence of benefit.

What happens when you take fenofibrates with a statin?

As for fenofibrates’ effect on the pharmacokinetics of statins, data are only available when combined with pravastatin and rosuvastatin for a small increase in AUC and Cmax. There are several theories explaining the increased risk of muscle toxicity when statins and fibrates are combined.

Are there any new niacin combos on the market?

In addition to removing the indication for coadministration with statins, the FDA is withdrawing from the market two niacin-statin combinations, Advicor and Simcor (AbbVie). The two drugs pair extended-release niacin with lovastatin and simvastatin, respectively.