What is reflection coefficient osmotic pressure?

Reflection coefficient (σ) – an index of the effectiveness of a solute in generating an osmotic driving force. ∆Π = RT Σ σs ∆C. s. • Tonicity – the concentration of effective solutes; the ability. of a solution to pull water across a biologic membrane.

What is the relationship between osmotic pressure and concentration?

The osmotic pressure of a solution is the pressure difference needed to stop the flow of solvent across a semipermeable membrane. The osmotic pressure of a solution is proportional to the molar concentration of the solute particles in solution.

How do you find the osmotic coefficient?

The osmotic coefficient, φ, was calculated according to Eqn [2.7. 16] by dividing the observed osmotic pressure by RTC (circles). The rational osmotic coefficient was obtained according to Eqn [2.7. 20] by dividing the observed osmotic pressure by −RT/VW ln XW (squares).

What is reflection coefficient in biology?

The irreversible thermodynamic parameter, sigma i, the reflection coefficient, is a measure of the relationship between the permeability of the solute and that of water. If a solute permeates by dissolution in the membrane, sigma i = 1.0; if it permeates by passage through an aqueous channel, sigma i < 1.0.

How is the osmotic coefficient of a solute calculated?

It is calculated as the product of solute concentration (e.g., in mmol/L) times the number of particles per mole in solution (i.e., whether the solute dissociates in solution). The extent of this dissociation is described by an osmotic coefficient called “g.” If the solute does not dissociate, g = 1.0.

What is the value of the reflection coefficient?

The value of the reflection coefficient can vary from 0 to 1.0 (Figure 1-1). When a = 1.0, the membrane is completely impermeable to the solute; the solute remains in the original solution and exerts its full osmotic pressure. When a = 0, the mem-

How is the Starling equation related to the theory of osmotic pressure?

Starling equation. The Starling equation describes these forces in mathematical terms. It is one of the Kedem–Katchalski equations which bring nonsteady state thermodynamics to the theory of osmotic pressure across membranes that are at least partly permeable to the solute responsible for the osmotic pressure difference (Staverman 1951;

What does Staverman’s reflection coefficient ( σ ) mean?

Staverman’s reflection coefficient (σ) corrects the actual colloid osmotic pressure difference to the observed or effective pressure. Since the discovery of the endothelial glycocalyx layer it is now helpful to think of σ as indicative of the effectiveness of the glycocalyx ultrafilter.