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What are the 12 hallmarks of cancer?

What are the 12 hallmarks of cancer?


  • 1.1 Self-sufficiency in growth signals.
  • 1.2 Insensitivity to anti-growth signals.
  • 1.3 Evading programmed cell death.
  • 1.4 Limitless replicative potential.
  • 1.5 Sustained angiogenesis.
  • 1.6 Tissue invasion and metastasis.

What are the 7 hallmarks of cancer?

We define seven hallmarks of cancer: selective growth and proliferative advantage, altered stress response favoring overall survival, vascularization, invasion and metastasis, metabolic rewiring, an abetting microenvironment, and immune modulation, while highlighting some considerations for the future of the field.

What are the 6 hallmarks of cancer?

The original six hallmarks are: self-sufficiency in growth signals, insensitivity to anti-growth signals, tissue invasion and metastasis, limitless replicative potential, sustained angiogenesis (blood vessel growth), and evasion of apoptosis (cell death).

What are the 8 hallmarks of cancer?

The eight distinct hallmarks consist of sustaining proliferative signaling, evading growth suppressors, resisting cell death, enabling replicative immortality, inducing angiogenesis, activating invasion and metastasis, deregulating cellular energetics and metabolism, and avoiding immune destruction.

Who are the authors of the hallmarks of cancer?

Cell, Vol. 100, 57–70, January 7, 2000, Copyright 2000 by Cell Press The Hallmarks of Cancer Review Cell, Vol. 100, 57–70, January 7, 2000, Copyright © 2000 by Cell Press The Hallmarks of Cancer Review Douglas Hanahan* and Robert A. Weinberg†

Where can I find the hallmarks of cancer?

D Hanahan 1 , R A Weinberg Affiliation 1Department of Biochemistry, Hormone Research Institute, University of California at San Francisco, 94143, USA. PMID: 10647931 DOI: 10.1016/s0092-8674(00)81683-9

Which is the best summary of Hanahan and Weinberg?

Reading many of the questions that some researchers ask in Researchgate, it seems that many of the questions can be answered by reading the two seminal publications of Hanahan and Weinberg. The summary here presented has a very simple intention: to promote the reading of these two publications.

What are the hallmarks of cancer in the next generation?

Hallmarks of cancer: the next generation Cell. 2011 Mar 4;144(5):646-74.doi: 10.1016/j.cell