What does granulomatous inflammation mean?

Granulomatous inflammation may be defined as a type of chronic inflammation in which a compact collection of cells of the mononuclear phagocyte system 37, chiefly activated macrophages and cells derived from them are predominant 1, 39.

What is a non Caseating granuloma?

Sarcoidosis is a disease of unknown cause characterized by non-necrotizing (“non-caseating”) granulomas in multiple organs and body sites, most commonly the lungs and lymph nodes within the chest cavity. Other common sites of involvement include the liver, spleen, skin, and eyes.

What is necrotizing granulomatous inflammation?

A necrotizing granuloma is an area of inflammation in which tissue has died. Necrotizing means dying or decaying. Tuberculosis and granulomatosis with polyangiitis are conditions that cause necrotizing granulomas.

What is epithelioid granuloma?

Epithelioid granulomas are a feature of chronic cutaneous leishmaniasis and leishmania recidivans though they have also been described in around 30% of cases of acute leishmaniasis. Although most cases of nodular post kala azar dermal leishmaniasis are non-granulomatous, epithelioid granulomas are seen in some cases.

What kind of cell is a sarcoid granuloma?

sarcoid granuloma the granuloma seen with sarcoidosis, consisting of multinucleated giant cells surrounded by macrophages and epithelioid cells derived from macrophages.

What kind of disease is granulomatous inflammation associated with?

Granulomatous inflammation of muscle is usually associated with sarcoidosis but can also be seen in infectious disease,148 inflammatory bowel disease, foreign body reactions, 149 thymoma, 150 lymphoma, 151 and myasthenia gravis. It may also occur without any evidence of systemic disease.

What does chronic granulomatous disease ( CGD ) mean?

Chronic granulomatous disease (CGD) is an inherited (genetic) immune system disorder that occurs when a type of white blood cell (phagocyte) that usually helps your body fight infections doesn’t work properly. As a result, the phagocytes can’t protect your body from bacterial and fungal infections.

Which is the best definition of a granuloma?

benign granuloma of thyroid chronic inflammation of the thyroid gland, converting it into a bulky tumor that later becomes extremely hard. coccidioidal granuloma the secondary stage of coccidioidomycosis. dental granuloma one usually surrounded by a fibrous sac continuous with the periodontal ligament and attached to the root apex of a tooth. 1.