What is the significance of Papez circuit?

A major loop circuit of the limbic system was originally discovered in the cat brain by Dr. James Papez in 1937. Together with other limbic-associated structures, the Papez circuit functions primarily in the cortical control of emotion and memory storage and contains centers that regulate aversion and gratification.

Is the Papez circuit the limbic system?

The Papez circuit is a fundamental component of the limbic system. It is a closed neural circuitry that starts and ends in the hippocampus. It is also known as the medial limbic circuit.

Which brain regions are included in Papez 1937 emotional Brain?

James Papez worked on the anatomical substrates of emotion and described a circuit, mainly composed of the hippocampus, thalamus and cingulum, and published his observations in 1937.

What is the mammillary bodies responsible for?

recollective memory
The primary function associated with the mammillary bodies is recollective memory. Memory information begins within the hippocampus. Theta waves activate CA3 neurons in the hippocampus. Information about memory transmits through the fornix to the mammillary bodies (orange line, Figure 1C).

Where does the last name Papez come from?

Historically, surnames evolved as a way to sort people into groups – by occupation, place of origin, clan affiliation, patronage, parentage, adoption, and even physical characteristics (like red hair). Many of the modern surnames in the dictionary can be traced back to Britain and Ireland. Where is the Papez family from?

Who was James Papez and what did he do?

He is most famous for his 1937 description of the Papez circuit which is a neural pathway in the brain thought to be involved in the cortical control of emotion. He was a neurologist at Cornell University and curator of the Wilder Brain Collection, when he published a journal article in which he outlined a “new” circuit to account for emotion.

When did James Papez propose the limbic system?

In 1937, James Papez proposed that the circuit connecting the hypothalamus to the limbic lobe was the basis for emotional experiences. Paul D. MacLean reconceptualized Papez’s proposal and coined the term limbic system.

Where does the Papez circuit begin and end?

The Papez circuit is a fundamental component of the limbic system. It is a closed neural circuitry that starts and ends in the hippocampus. It is also known as the medial limbic circuit. Article: