What drugs cause fixed eruptions?

The major categories of causative agents of fixed drug eruption include antibiotics, antiepileptics, nonsteroidal anti-inflammatory agents, sildenafil, and phenothiazines, although numerous other agents and certain foods such as cashews and licorice have also been reported as causative agents.

How do you fix a fixed drug eruption?

The main goal of treatment is to identify the causative agent and avoid it. Treatment for fixed drug eruptions (FDEs) otherwise is symptomatic. Systemic antihistamines and topical corticosteroids may be all that are required. In cases in which infection is suspected, antibiotics and proper wound care are advised.

Is fixed drug eruption curable?

Fixed drug eruptions (FDE) are a distinct type of drug eruptions that appear as pruritic, well circumscribed, round or oval-shaped, erythematous macules or edematous plaques, and characteristically recur at the same sites upon re-exposure to the offending drug. They usually resolve spontaneously with hyperpigmentation.

What’s a fixed drug eruption?

Fixed drug eruption (FDE) is a distinctive type of cutaneous drug reaction that characteristically recurs in the same locations upon reexposure to the offending drug.

What causes a fixed drug eruption?

Medications can cause many skin reactions. This particular appearance is called a “fixed drug eruption” and was caused by a reaction to ceftazidime. This type of reaction typically recurs in exactly the same location when the person takes the same medication again.

Which medications may cause drug eruptions?

Drugs that cause a fixed drug eruption Paracetamol /phenacetin and other pain killers Tetracycline antibiotics; doxycycline, minocycline Sulphonamide antibiotics including trimethoprim + sulphamethoxazole, sulfasalazine Acetylsalicylic acid/aspirin Nonsteroidal anti-inflammatories ( NSAIDs) including ibuprofen Sedatives including barbiturates, benzodiazepines and chlordiazepoxide

What is fixed drug reaction?

Fixed drug reaction. Fixed drug reactions, are common and so named because they recur at the same site with each exposure to a particular medication. Medications inducing fixed drug eruptions are usually those taken intermittently.

What is the disease of drug eruption?

Bullous drug eruptions (immunobullous disease is important to recognise, as drug withdrawal leads to clearance) Drug-induced lupus erythematosus. A drug eruption is sometimes, unnecessarily, called a cutaneous drug eruption. Drugs can also cause: Drug-induced skin pigmentation