Does daptomycin cover enterococcus?

Does daptomycin cover enterococcus?

Abstract. Daptomycin is one of the few treatment options for infections caused by enterococci that are resistant to ampicillin and vancomycin, such as vancomycin-resistant Enterococcus faecium.

What antibiotic is used for enterococci infection in infectious endocarditis?

Ampicillin plus ceftriaxone is as effective as ampicillin plus gentamicin for treating enterococcus faecalis infective endocarditis.

Is E faecalis resistant to daptomycin?

E. faecalis V583 is a member of an enterococcal clonal complex associated with hospital infection outbreaks and endemicity (61) and is vancomycin resistant (62) but daptomycin sensitive (MIC = 2 μg/ml).

What antibiotics treat Enterococcus faecalis?

Ampicillin is the preferred antibiotic used to treat E. faecalis infections. Other antibiotic options include: daptomycin.

Is there an ABX guide for Daptomycin?

Daptomycin is a topic covered in the Johns Hopkins ABX Guide. To view the entire topic, please sign in or purchase a subscription. Official website of the Johns Hopkins Antibiotic (ABX), HIV, Diabetes, and Psychiatry Guides, powered by Unbound Medicine. Johns Hopkins Guide App for iOS, iPhone, iPad, and Android included.

How is beta lactam used to treat Enterococcus faecalis?

Double beta-lactam therapy for Enterococcus faecalis Given the rise of E. faecalis with high-level aminoglycoside resistance (HLAR), as well as significant toxicities associated with these agents, recent endocarditis studies have investigated the use of double beta-lactam therapy as a novel treatment approach.

What kind of infections can be caused by daptomycin?

S. aureus bacteremia, including those with right-sided endocarditis, caused by MSSA and MRSA Endocarditis caused by Enterococcus spp. resistant to vancomycin, penicillin and aminoglycosides [2] VRE infections including BSI, intra-abdominal infections, urinary tract infections, SSTI

Are there any antibiotics that are effective against enterococci?

Enterococci also have a native resistance to clinically achievable concentrations of aminoglycosides, which precludes their use as single agents. Although E. faecalisis naturally resistant to quinupristin-dalfopristin, this combination is highly active against E. faeciumstrains that lack specific resistance determinants.