What are the differences between somatic gene therapy and germline gene therapy?

What are the differences between somatic gene therapy and germline gene therapy?

Unlike germline therapy, somatic gene therapy involves the insertion of therapeutic DNA into body cells, rather than germ cells or gametes. This means that any effects of the therapy are confined to the individual being treated and are not inherited by future offspring.

What is the difference between somatic and germline cells?

“Somatic cells” is a fairly general term which refers to essentially all the cells of the body except for the germ line; the germ line being the cells in the sexual organs that produce sperm and eggs. So anything that doesn’t have the job of producing sperm or eggs is a somatic cell.

What are the differences in the two types of gene therapy?

Somatic cell gene therapy only effects the other body cells. Somatic cell gene therapy has to be done several times over the coarse of the patient’s life because the effects do not last very long. The contrast of somatic cell gene therapy is germline therapy. Germline therapy takes place in the reproductive cells.

What is somatic cell therapy?

Somatic cell gene therapy involves the placement of a human gene into a living person’s somatic cells—cells that do not produce the eggs and sperm that in turn produce the next generation. Somatic cell gene therapy would aim to cure a disease only in the patient, not in the patient’s descendants.

What are the main differences between somatic and germ cells?

What is the difference between Somatic and Germ Cells? Definition of Somatic and Germ Cells: Somatic cell is any cell of a multicellular organism with the exception of the cells that are predestined to form gametes or germ-line cells. Germ cell is a cell that have one set of chromosome and have the ability to transfer genetic information to next generations.

What are the two main types of gene therapy?

The two gene therapy types are germ line gene therapy and somatic gene therapy.

What are some examples of gene therapy?

An example of the successful use of gene therapy in humans is in the treatment of adenosine deaminase (ADA) deficiency. ADA deficiency is an autosomal recessive disease that causes severe combined immunodeficiency ( SCID ) in sufferers.

What is an example of somatic therapy?

For example, somatic therapy can help a patient determine whether they are distracted because of a stress trigger or because of something new and interesting in their environment. A therapist can apply traditional ADHD treatment therapies, such as executive functioning skills training, to help a patient who is experiencing the latter.