How do you calculate APRI?

The formula for the APRI score is [(AST/upper limit of the normal AST range) X 100]/Platelet Count….How Is It Calculated?

1. Divide your AST count by the upper limit of the normal AST range. Most experts say that 40 is a good value to use here.
2. Multiply that answer by 100.
3. Divide that answer by your platelet count.

What is platelet ratio index?

Determines the likelihood of hepatic fibrosis and cirrhosis in patients with hepatitis C. Pearls/Pitfalls. Why Use. Patients with hepatitis C being considered for liver biopsy to determine chance of fibrosis or cirrhosis.

What is top normal AST?

The platelet count is measured in platelets/cubic millimeter. The upper limit of the normal range (ULN) of the AST, is usually set to 40 or 42 IU/L. The formula divides your AST by the Upper Limit of the Normal Range (40 or 42). Then it multiplies that result by 100.

How accurate is APRI score?

Interpretation: In a meta-analysis of 40 studies, investigators concluded that an APRI score greater than 1.0 had a sensitivity of 76% and specificity of 72% for predicting cirrhosis.

How to calculate Apri for a platelet count?

■ Platelet count measured in 10 9 cells per L. The formula used to calculate the index is: APRI = AST (IU/L) / AST upper normal limit (IU/L) /Platelet count (10 9/L) x 100. The use of the index can reduce unnecessary liver biopsy investigations in patients who are deemed to carry a low risk of liver fibrosis.

How to calculate the AST to platelet ratio index?

AST to Platelet Ratio Index (APRI) Calculator. APRI = AST Level (IU/L) AST (Upper Limit of Normal) (IU/L) Platelet Count (109/L) x 100 = Interpretation: In a meta-analysis of 40 studies, investigators concluded that an APRI score greater than 1.0 had a sensitivity of 76% and specificity of 72% for predicting cirrhosis.

When to set a higher platelet count for women?

Higher platelet count was set when platelet count >405 × 10 9 /L or >379 × 10 9 /L for women ≤64 or >64 years of age, respectively; and platelet count >362 × 10 9 /L or >350 × 10 9 /L for men ≤64 or >64 years of age, respectively (data from reference 9 ).

How is the fib 4 platelet count calculated?

Platelet count is used to identify whether there are sufficient clotting particles (those produced by liver) and thus indirectly test liver function. This score employs the following equation: FIB 4 = (Age x AST) / (Platelet count x √ALT)