How do you test for Langerhans Cell Histiocytosis?

Testing for Langerhans cell histiocytosis (LCH) may include bronchoscopy with biopsy , x-ray , skin biopsy, bone marrow biopsy, complete blood count, skeletal X-rays survey, pulmonary function tests and liver funcion tests, as well as MRI and CT scanning of the head to evaluate possible abnormalities of the …

What does LCH do to bones?

In about 8 out of 10 people, LCH leads to tumors called granulomas in the skull and in other bones. That can cause pain and swelling, and sometimes it can fracture your arms or legs. LCH symptoms can range from mild to more serious. Some people are born with it, and the disease eventually goes away on its own.

Is histiocytosis X curable?

Most children are cured from LCH. There is a 90 per cent survival rate. About a quarter of children with multi-system disease have the disease reactivate after stopping treatment and need to be treated again. Treatment is effective even if it has to be started again.

What are Langerhans cells?

Langerhans cell. n. An antigen-presenting dendritic cell of the epidermis, containing characteristic rod-shaped granules (Birbeck granules). Langerhans cells are thought to stimulate T cells in lymph nodes to which they migrate and also T cells in the skin.

What is the Langerhans cell?

Definition of Langerhans cell : a cell found in the epidermis that functions as an antigen-presenting cell which binds antigen entering through the skin

What do Langerhan cells mean?

Definition of Langerhans cell : a cell found in the epidermis that functions as an antigen-presenting cell which binds antigen entering through the skin

Is histiocytosis cancer?

Langerhans cell histiocytosis is a type of cancer that can damage tissue or cause lesions to form in one or more places in the body. Langerhans cell histiocytosis ( LCH ) is a rare cancer that begins in LCH cells. LCH cells are a type of dendritic cell which fights infection.