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Are osteoprogenitor cells stem cells?

Are osteoprogenitor cells stem cells?

Osseointegration starts with osteoprogenitor cells (stem/stromal cells that have the ability to differentiate into osteoblasts, the main cell type constituting bone tissue) being attracted to the implant at later stages of the immune response.

What is the role of Osteoprogenitor cell?

Osteoprogenitor cells are the ‘stem’ cells of bone, and are the source of new osteoblasts. Osteocytes maintain bone tissue. Fine processes from these cells ramify through bone, and form gap junctions with other osteocytes.

Where are osteoprogenitor cells found?

Osteoprogenitor cells are located on the endosteal and periosteal surface of the bone and inner surface of the Haversian canals (see Fig. 6.7). Some osteoprogenitor cells transform into osteoblasts after being divided by mitosis.

Are osteoprogenitor cells found in the Endosteum?

Osteoclasts can also be present in the endosteum in regions of active bone resorption. The endosteum contains osteoprogenitor cells but does not appear to contain either MSCs or hematopoietic stem cells (HSCs).

Are osteoblast cells immature bone cells?

Osteoblasts are mononucleate cuboid cells that are responsible for bone formation. Osteoblasts originate from immature mesenchymal stem cells, which can also differentiate and give rise to chondrocytes, muscle, fat, ligament and tendon cells (Aubin and Triffitt, 2002 ).

Are bone cells called osteocytes?

Osteocyte, a cell that lies within the substance of fully formed bone. It occupies a small chamber called a lacuna, which is contained in the calcified matrix of bone. Osteocytes derive from osteoblasts , or bone-forming cells, and are essentially osteoblasts surrounded by the products they secreted.

Do osteoblasts form from mesenchymal cells?

Osteoblasts are the major cellular component of bone. Osteoblasts arise from mesenchymal stem cells (MSC). MSC give rise to osteoblasts, adipocytes, and myocytes among other cell types. Osteoblast quantity is understood to be inversely proportional to that of marrow adipocytes which comprise marrow adipose tissue (MAT).