Why does creatinine clearance overestimate GFR?

Creatinine clearance exceeds GFR because creati- nine is secreted by the proximal tubule as well as filtered by the glomerulus. Creatinine clearance can be measured from serum creatinine and cre- atinine excretion, or estimated from serum cre- atinine using estimating equations.

What is the normal for GFR?

in adults, the normal gFR number is more than 90. For more information, see chart on the bottom of page 2. gFR declines with age, even in people without kidney disease. If your GFR is between 60 and 89…

What is the formula for GFR?

Your GFR tells you how much kidney function you have. It is defined as the sum of the filtration rates of all your functioning nephrons (filtering units making up the kidneys). An estimate of the normal value for your GFR can be obtained by using the equation: GFR = 140 – [your age].

What are the factors of GFR?

Both glomerular capillary hydrostatic pressure and renal blood flow are important determinants of the glomerular filtration rate (GFR).

How is glomerular filtration rate ( GFR ) calculated?

Glomerular Filtration Rate (GFR) What is GFR? GFR – glomerular filtration rate is the best test to measure your level of kidney function and determine your stage of kidney disease. Your doctor can calculate it from the results of your blood creatinine test, your age, body size and gender.

What does a low GFR mean for kidney disease?

Your GFR tells your doctor your stage of kidney disease and helps the doctor plan your treatment. If your GFR number is low, your kidneys are not working as well as they should. The earlier kidney disease is detected, the better the chance of slowing or stopping its progression. What are the Stages of Chronic Kidney Disease (CKD)?

Can a GFR be adjusted for body surface area?

The GFR estimating equations on this page will automatically adjust for body surface area unless “yes” is selected for “remove body surface adjustment.” Drug dosing should be based on GFR which is not adjusted for body surface area. For persons under 18 years of age, use the pediatric GFR calculator. Is it CKD?

What does it mean when your EGFR is above 60?

A eGFR below 60 for three months or more or a eGFR above 60 with kidney damage (marked by high levels of albumin in your urine) indicates chronic kidney disease. Your doctor will want to investigate the cause of your kidney disease and continue to check your kidney function to help plan your treatment.