What is the use of prostaglandin?

PIP: Prostaglandins have found clinical applications in: 1) termination of midtrimester pregnancy; 2) induction of labor; 3) menstrual regulation; and 4) control of postpartum hemorrhage.

Are prostaglandins toxic?

Toxicity. When prostaglandin E2 (PGE2) is given in excess, hyper-stimulation of the uterus occurs and immediate discontinuation of the drug usually results in resolution of toxic effects. If symptoms continue a beta adrenergic drug (e.g. terbutaline) can be used.

Which is the most common side effect associated with prostaglandin analogues for the treatment of glaucoma?

Prostaglandin analogs have distinctive local adverse reactions, including eyelash bristling/lengthening, eyelid pigmentation, iris pigmentation, and upper eyelid deepening.

Why are prostaglandins contraindicated in pregnancy?

Prostaglandin E2 is contraindicated in patients with a known hypersensitivity to prostaglandins. As an oxytocic agent, prostaglandin E2 should be avoided in scenarios in which vaginal delivery or the induction of labor is contraindicated and should be stopped before administering oxytocin.

How do prostaglandin E1 analogues work?

How do prostaglandin E1 analogues work? Prostaglandin E1 analogues are a class of medication that includes the medication alprostadil (Caverject ® and MUSE ®). Alprostadil works by mimicking prostaglandin , a chemical in the penis that begins the chemical “cascade” that normally causes an erection due to the signal from the brain. It relaxes the smooth muscle of the penis, allowing more blood to flow into the penis and produce an erection.

How do prostaglandin analogs work?

Prostaglandin analogues, also called prostaglandin analogs, are a type of medication prescribed to lower intraocular pressure, or pressure within the eye. A doctor may prescribe them to patients with glaucoma or ocular hypertension. They work by reducing the accumulation of aqueous humor, or eyeball fluid, in order to lower the pressure.

What are prostaglandin inhibitors?

Prostaglandin inhibitors are drugs that act on lipid compounds known as prostaglandins, found throughout the body to regulate muscle contractions and related activities. The body produces them locally, and while they are chemical messengers, they are not classified as hormones.