What is pulmonary tuberculosis relapse?

TB relapse is defined as a patient who has become (and remained) culture negative while receiving therapy but after completion of therapy becomes: Culture positive again or. Has clinical or radiographic deterioration that is consistent with active tuberculosis.

What can be a reason for tuberculosis to reoccur in a patient?

Recurrence of tuberculosis (TB) can be due to a regrowth of the same strain of Mycobacterium tuberculosis that caused the previous TB episode, known as relapse, or reinfection through a different strain.

Can pulmonary TB reoccur?

The highest relapse rate occurred with sputum smear-positive pulmonary TB (12.37%), followed by sputum smear-negative pulmonary TB (8.72%) and extrapulmonary TB (6.05%). More relapsed patients (15.89%) had used medicines from Group 2 to Group 5, compared to patients using Group 1 medicines (9.31%).

Can tuberculosis come back after treatment?

Of 144 TB patients with complete covariate data, 43 (30%) had a recurrence one to two years, 73 (51%) had a recurrence one to three years, and 108 (75%) had a recurrence one to five years, after completing anti-TB therapy. TB = tuberculosis.

How many people have relapsed from pulmonary tuberculosis?

Five hundred forty-three patients with bacteriologically confirmed pulmonary tuberculosis who successfully completed treatment were followed for 5 years to determine relapse rates and to see whether any factors could be said to predispose to relapse. Practically the entire treatment of these patients had been carried out in their homes.

What is the definition of a TB relapse?

TB relapse is defined as a patient who has become (and remained) culture negative while receiving therapy but after completion of therapy becomes: Has clinical or radiographic deterioration that is consistent with active tuberculosis.

Is there a recurrence of tuberculosis after treatment?

A recurrence of tuberculosis is a second episode of tuberculosis occurring after a first episode had been considered cured. The 2-year incidence of recurrence after treatment of pulmonary tuberculosis with rifampicin-containing regimens ranges from 0–27%.

When does treatment failure for pulmonary tuberculosis occur?

[AIII] Treatment failure is the presence of continued or recurrently positive cultures during the course of antituberculosis therapy. After 3 months of multi-drug therapy for pulmonary tuberculosis caused by drug susceptible organisms, 90–95% of patients will have negative cultures and show clinical improvement.