Useful tips

What does an elevated CA 15-3 mean?

What does an elevated CA 15-3 mean?

In metastatic breast cancer, the highest levels of CA 15-3 often are seen when the cancer has spread to the bones and/or the liver. Increasing concentrations of CA 15-3 over time may indicate that a person is not responding to treatment or that the cancer is recurring.

How accurate is tumor marker CA 15-3?

Sensitivity and specificity for CA 15-3 were 65.7% and 76.6%, for CEA 37.5% and 77.7% and for CA 125 93.8% and 28.7%, respectively. CA 15-3 is a marker with definite diagnostic accuracy compared to CEA and CA 125 in breast cancer EF.

What is CA 15-3 marker?

This test measures the amount of cancer antigen 15-3 (CA 15-3) in your blood. CA 15-3 is a substance that stimulates your body’s defense system. Some kinds of cancer cells release the CA 15-3 antigen into the blood. This test is used to monitor certain types of cancer.

Why is my cancer marker high?

Tumor marker levels may be higher when there is cancer in the body. They are not very “specific,” meaning non-cancer health issues can also cause these levels to be higher. They must be used along with radiology tests and exams by your healthcare provider.

What does CA 15-3 stand for in cancer marker?

CA 15-3 stands for cancer antigen 15-3 which is a protein produced by normal breast cells. Some people – not all – with cancerous breast tumors have an increased production of CA 15-3.

Are there any problems with the CA 15-3 test?

The problem with the CA 15-3 test is that it is not all that reliable, particularly for early breast cancer. One source indicated that CA 15-3 is elevated in only about 10% of women with early localized breast cancer, while another source indicated the figure was 30%.

Is the CA 15-3 antigen linked to breast cancer?

The CA 15-3 antigen is a protein released into the bloodstream by certain types of cancer. Although breast cancer is closely linked to the CA 15-3 antigen, it is associated with other cancerous and non-cancerous conditions as well. CA 15-3 is one of several substances classified as tumor markers, which may increase as a malignancy progresses

How is the Cancer Antigen 15-3 biomarker test used?

Interpreting Results The cancer antigen 15-3 (CA 15-3) biomarker test is used to monitor breast cancer. The CA 15-3 antigen is a protein released into the bloodstream by certain types of cancer. Although breast cancer is closely linked to the CA 15-3 antigen, it is associated with other cancerous and non-cancerous conditions as well.