How often can you have EYLEA injections?

EYLEA is the only FDA-approved treatment for Wet AMD with a recommended dose of 2 mg administered by injection in the eye every 4 weeks (approximately every 28 days, monthly) for the first 3 months, followed by injection once every 8 weeks (2 months).

How is aflibercept administered?

Aflibercept injection comes as a solution (liquid) to be injected into the eye by a doctor. It is usually given in a doctor’s office. Your doctor will give you injections on a schedule that is best for you and your condition.

How many injections are needed for wet macular degeneration?

You may need injections every four to six weeks to maintain the beneficial effect of the medication. In some instances, you may partially recover vision as the blood vessels shrink and the fluid under the retina absorbs, allowing some vision gain.

Does Medicare cover EYLEA injections?

Medicare pays for an intravitreal injection (which is considered a minor surgery) as part of a global surgical package that includes the preoperative, intraoperative, and postoperative services routinely performed by the physician. Medicare pays for Eylea and Lucentis separately from the intravitreal injection.

How often do I need to take aflibercept?

Although monthly dosing may continue, additional efficacy was not demonstrated in most patients dosed every 4 weeks vs. every 8 weeks in chronic use. However, some patients may continue to require every 4 week (monthly) dosing after the first 3 months.

How often to take aflibercept for diabetic retinopathy?

For the treatment of diabetic macular edema (DME) and diabetic retinopathy. 2 mg (0.05 mL) by intravitreal injection every 4 weeks (approximately every 28 days, monthly) for the first 20 weeks (5 months), followed by 2 mg via intravitreal injection every 8 weeks.

How much Aflibercept is in an intravitreal injection?

The intravitreal injection should be performed with a 30-gauge × ½-inch injection needle (not provided). The pre-filled syringe contains more than the recommended dose of 2 mg aflibercept (equivalent to 50 microliters). The excess volume must be discarded prior to the administration.

Are there any side effects to taking aflibercept?

Aflibercept is contraindicated in patients with active intraocular inflammation. Use with caution in patients with a history of glaucoma. Increased intraocular pressure (IOP) has occurred within 60 minutes of aflibercept injection in some patients. Sustained increased IOP has also been reported after repeated dosing of intravitreal VEGF inhibitors.