Useful tips

Are there any treatments for Smith-Magenis syndrome?

Are there any treatments for Smith-Magenis syndrome?

To our knowledge this pattern is distinctive to persons with SMS and not found elsewhere. SMS therefore offers a unique human syndrome for the study of melatonin function. At the present time, there is no effective treatment for sleep disturbances in SMS.

What is the life expectancy of someone with Smith-Magenis syndrome?

However it is known that there was an adult with SMS who lived until she was 88 years old, and there are several adults with SMS in their 40’s and 50’s. It is believed that unless there is additional medical complications, life expectancy should not be impacted upon.

Is Smith-Magenis syndrome a neurological disorder?

Smith-Magenis syndrome is a complex neurodevelopmental disorder that includes intellectual deficiency, speech delay, behavioral disturbance and typical sleep disorders.

Is Smith-Magenis syndrome a disability?

Smith-Magenis syndrome is a developmental disorder that affects many parts of the body. The major features of this condition include mild to moderate intellectual disability, delayed speech and language skills, distinctive facial features, sleep disturbances, and behavioral problems.

How to help someone with Smith Magenis syndrome?

Individuals with SMS often have a good sense of humor and enjoy jokes and gentle teasing. Funny expressions convey concepts in an upbeat way while prompting appropriate behaviors. For more Behavior Support Strategies purchase a copy of PRISMS On the Road to Success with SMS: A Smith-Magenis Guidebook for Schools.

How many people have Smith Magenis syndrome ( SMS )?

Smith-Magenis syndrome (SMS) is one in many examples of this complexity. SMS is linked to a microdeletion of chromosome 17 in 90 % of the cases, and entails major behavioral disorders that jeopardize the social outcomes of the patients [ 1 – 4 ]. Its prevalence is estimated at 1 in 25,000, although this data may be an underestimation [ 5 ].

What to do about behavioral disturbance in Smith?

In any case, efforts should focus on improving communication skills, identifying and treating attention deficit/hyperactivity, aggressiveness and anxiety.

Where does the deletion occur in Smith Magenis syndrome?

Most people with Smith-Magenis syndrome (SMS) have a deletion of genetic material from a specific region of chromosome 17. The deletion is not usually inherited, occurring randomly during the formation of egg or sperm cells in a parent, or in early embryonic development.