Which calcium channel blockers are dihydropyridine?

Dihydropyridines bind to L-type calcium channels in the vascular smooth muscle, which results in vasodilatation and a decrease in blood pressure. They are effective as monotherapy in black patients and elderly patients. Some examples of dihydropyridines include amlodipine, nifedipine, clevidipine, and felodipine.

What are long acting dihydropyridine calcium channel blocker?

Calcium Channel Blockers Long-acting dihydropyridines (e.g., extended release nifedipine, amlodipine) have been shown to be safer anti-hypertensive drugs, in part, because of reduced reflex responses. This characteristic also makes them more suitable for angina than short-acting dihydropyridines.

What is the difference in dihydropyridine and non-dihydropyridine calcium channel blockers?

The dihydropyridines are more vascular selective and the non-dihydropyridines are more myocardial selective and tend to reduce the heart rate. Further important differences are between short- and long- acting forms of the calcium channel antagonists.

Which agent is a non-dihydropyridine calcium channel blocker?

The Non-dihydropyridine CCBs such as verapamil (Isoptinā) and diltiazem (Cardizemā) cause less vasodilation and more cardiac depression than dihydropyridine CCBs. They have negative effects at the SA and AV nodes, and cause reductions in heart rate and contractility.

What are side effects of calcium blocker?

Side Effects. Side effects of calcium channel blockers can include: Lightheadedness. Low blood pressure. Slower heart rate. Drowsiness. Constipation.

Do calcium blockers hurt bones?

Calcium channel blockers do not affect mineralization of the bone, nor do they increase the risk for osteoporosis. One group found that people on calcium channel blockers may have a slightly higher risk of fractures; however, that was thought to be due to an increased number of falls, especially in the elderly.

What is a calcium blocker?

Medical Definition of calcium channel blocker. : any of a class of drugs (as verapamil ) that prevent or slow the influx of calcium ions into smooth muscle cells especially of the heart and that are used especially to treat some forms of angina pectoris and some cardiac arrhythmias. — called also calcium blocker.