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What is the difference between ECMO and ECPR?

What is the difference between ECMO and ECPR?

As discussed previously, the primary goal of ECMO is to stabilize hemodynamics, restore oxygen delivery and carbon dioxide removal and maintain normothermic physiologic processes to promote healing. The primary goal of ECPR is to address the reperfusion injury issue while preventing the patient’s immediate death.

What is ECMO success rate?

Most patients who require extracorporeal membrane oxygenation (ECMO) for severe COVID-19 survive, according to an international registry. Estimated 90-day in-hospital mortality was 37.4%, and mortality among those who completed their hospitalization (final disposition of death or discharge) was 39%.

What is retrograde flow in ECMO?

Because of the retrograde flow support in the setting of peripheral VA-ECMO, blood travels in the direction opposite to normal; retrograde from the femoral or iliac artery back toward the thoracic aorta.

When do you use ECPR?

Extracorporeal cardiopulmonary resuscitation (ECPR) refers to the use of rapid-deployment venoarterial extracorporeal membrane oxygenation to provide circulatory support during cardiac arrest, when conventional CPR has failed to provide return of spontaneous circulation (ROSC) [1], [2], or when repetitive arrests occur …

How much blood flow does an ECMO circuit handle?

The typical adult ECMO circuit handles anywhere between 1-6 litres per minute of blood flow, so large bore cannulas are needed to accommodate this. The key points about the drainage and return cannulas are:

What does ECMO stand for in cardiac arrest?

As a method of circulating blood during cardiac arrest, ECMO has now been dubbed “extracorporeal life support (ECLS)” or “extracorporeal cardiopulmonary resuscitation (ECPR)” and can achieve physiologic levels of blood flow while the heart is stopped.

What should the systemic oxygen saturation be for ECMO?

Hence, if the mixed venous oxygen saturation is 60%, and assuming the oxygenator is working correctly and providing 100% saturated ECMO blood, then your systemic oxygen saturation would be around 80%

What are the survival rates for ECMO patients?

Several observational studies and uncontrolled clinical trials of patients with severe acute respiratory failure reported survival rates from 50 to 71 percent among patients who received ECMO compared with historical control rates [ 2-10,14-16 ].