What does chromosome 16 indicate?

Chromosome 16 contains thousands of genes. The role of these genes is to guide protein production, which impacts a variety of functions in the body. Unfortunately, many genetic conditions are related to problems with the genes on chromosome 16.

What does the 16th chromosome control?

Chromosome 16 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 16 spans about 90 million base pairs (the building material of DNA) and represents just under 3% of the total DNA in cells….

Can chromosomal deletions be modeled?

Mouse models that carry engineered chromosomal deletions have been successfully used to model the human chromosomal deletions that are responsible for DGS (59, 60, 69), Prader-Willi syndrome (PGS) (117), and SMS (122, 123).

What happens if your missing chromosome 16?

A chromosome 16 deletion is a rare genetic condition in which part of the genetic material is missing that makes up chromosome 16, one of the body’s 46 chromosomes. Like most other chromosome disorders, this increases the risk of birth defects, developmental delay and learning difficulties.

How many genes are found in Mus musculus?

It also develops age-related hearing loss. 75% of the mouse genes are in 1:1 orthologous relationships to human genes and have most likely maintained their ancestral function in both species. The reference proteome of Mus musculus is derived from the genome sequence of strain C57BL/6J that was published in 2009. The size of the genome is 2.6 Gb.

Which is A consomic strain of Mus musculus?

Church DM, et al. PLoS Biol 2009 May 5 Mouse consomic strains: exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies. Gregorová S, et al. Genome Res 2008 Mar mtDNA phylogeny and evolution of laboratory mouse strains. Goios A, et al. Genome Res 2007 Mar

What are unique mutations in mitochondrial DNA ( Sam ) strains?

Unique mutations in mitochondrial DNA of senescence-accelerated mouse (SAM) strains. Mizutani J, et al. J Hered 2001 Jul-Aug tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence.

What are the components of Mus musculus UniProt?

Components i Component name Genome Accession (s) Proteins Chromosome 1 CM000994 CM000994 3195 Chromosome 2 CM000995 CM000995 4044 Chromosome 3 CM000996 CM000996 2523 Chromosome 4 CM000997 CM000997 2952