How Filgrastim is produced?

Filgrastim is produced by bacteria through the use of genetic engineering and recombinant DNA technology. Filgrastim belongs to a class of drugs called colony-stimulating factors because of their ability to stimulate cells in the bone marrow to multiply and form colonies of new cells.

Is Filgrastim the same as NEUPOGEN?

NEUPOGEN (filgrastim) is a 175 amino acid human granulocyte colony-stimulating factor (G-CSF) manufactured by recombinant DNA technology. NEUPOGEN is produced by Escherichia coli (E coli) bacteria into which has been inserted the human granulocyte colony-stimulating factor gene.

How do you administer NEUPOGEN IV?

The recommended starting dosage of NEUPOGEN is 5 mcg/kg/day‚ administered as a single daily injection by subcutaneous injection‚ by short intravenous infusion (15 to 30 minutes)‚ or by continuous intravenous infusion.

How is NEUPOGEN made?

NEUPOGEN® is a 175 amino acid protein manufactured by recombinant DNA technology. 1 NEUPOGEN® is produced by Escherichia coli (E coli) bacteria into which has been inserted the human granulocyte colony-stimulating factor gene. NEUPOGEN® has a molecular weight of 18‚800 daltons.

How much Filgrastim is in Neupogen 30 mu?

Name of the medicinal product Neupogen Singleject 30 MU (0.6 mg/ml) solution for injection in a pre-filled syringe 2. Qualitative and quantitative composition Each pre-filled syringe contains 30 million units (MU)/300 micrograms (μg) of filgrastim in 0.5 ml (0.6 mg/ml).

How big is a syringe of Neupogen?

NEUPOGEN is a clear, colourless solution. It is supplied in pre-filled syringes or vials. The syringes and vials are packed in cartons of 10 and are available in the following strengths: 300 micrograms of filgrastim in a volume of 0.5 mL, in a syringe; 480 micrograms of filgrastim in a volume of 0.5 mL, in a syringe;

How much Filgrastim is in a 30 ml syringe?

Each pre-filled syringe contains 30 million units (MU)/300 micrograms (μg) of filgrastim in 0.5 ml (0.6 mg/ml).

How does filgrastim work to treat neutropenic fever?

Filgrastim (Neupogen®) is a Supportive Care Therapy to prevent or treat Neutropenic Fever. How does filgrastim (Neupogen®) work? Filgrastim (Neupogen®) is designed to lower risk of infection after chemotherapy. It is part of a family of drugs called “granulocyte colony-stimulating factor” (G-CSF), or growth factor.