Guidelines

Which part of withania somnifera is used?

Which part of withania somnifera is used?

Ashwagandha, scientifically known as Withania somnifera Dunal, is an important medicinal plant in the Ayurvedic system of medicine. The roots are highly valued, and are used either alone or in combination with other medicinal plants to treat a variety of ailments.

What do Withanolides do?

Withanolides is a series of small molecules widely found in Solanaceae. The solanaceae plant is traditionally used to treat asthma, parasitic disease, constipation, edema, glaucoma, headache, hepatopathy, reducing swelling and inflammation, postpartum pain, skin diseases [2-4].

Is Withanolides a steroid?

Withanolides are a group of at least 300 naturally occurring steroids built on an ergostane skeleton. They occur as secondary metabolites primarily in genera of the Nightshade family, for example in the tomatillo.

Does ashwagandha have side effects?

The long-term safety of ashwagandha is not known. Large doses of ashwagandha might cause stomach upset, diarrhea, and vomiting. Rarely, liver problems might occur. When applied to the skin: There isn’t enough reliable information to know if ashwagandha is safe or what the side effects might be.

What kind of plant is rich in withanolides?

Withania somnifera, a multipurpose medicinal plant is a rich reservoir of pharmaceutically active triterpenoids that are steroidal lactones known as withanolides.

What kind of plant is Withania somnifera?

Withania somnifera (Solanaceae) commonly known as ashwagandha or Indian ginseng, is a valued medicinal plant known since antiquity (~3000 years; Winters, 2006 ). It is a commended genus described in the Indian Ayurvedic system of medicine and also enlisted as an important herb in Unani and Chinese traditional medicinal systems.

How are withanolides and ashwagandha used in medicine?

Withanolide A The withanolides serve as important hormone precursors that can convert into human physiologic hormones as needed. Ashwagandha is thought to be amphoteric; i.e., it can help regulate important physiologic processes.

How are genes involved in biosynthesis of withanolide?

Though the plant has been well-characterized in terms of phytochemical profiles as well as pharmaceutical activities, limited attempts have been made to decipher the biosynthetic route and identification of key regulatory genes involved in withanolide biosynthesis.