What is the mechanism of action for albuterol?

Mechanism of Action Albuterol acts on beta-2 adrenergic receptors to relax the bronchial smooth muscle. It also inhibits the release of immediate hypersensitivity mediators from cells, especially mast cells.

What is the chemical class of albuterol?

Albuterol belongs to a class of drugs known as bronchodilators. It works in the airways by opening breathing passages and relaxing muscles.

What happens to albuterol when heated?

Albuterol inhalers for asthma can explode when stored in temperatures over 120 degrees; even in moderately high temperatures, they deliver less of the chemical than when they are stored at room temperature.

What are the complications of albuterol?

Side effects of albuterol include nervousness or shakiness, headache, throat or nasal irritation, and muscle aches. More-serious — though less common — side effects include a rapid heart rate (tachycardia) or feelings of fluttering or a pounding heart (palpitations).

What is the mechanism of action of albuterol sulfate?

Albuterol Sulfate Mechanism of Action: The prime action of β-adrenergic drugs is to stimulate adenyl cyclase, the enzyme that catalyzes the formation of cyclic-3′,5′-adenosine monophosphate (cAMP) from adenosine triphosphate (ATP). The cAMP thus formed mediates the cellular responses.

Where does albuterol take place in the body?

Albuterol is a short-acting agonist at Beta-2 receptors mainly located in the bronchial smooth muscle of respiratory tract and smooth muscle of blood vessels. Albuterol starts acting in about 1 to 5 minutes and can be effective for a duration of 3 to 4 hours.

How does albuterol work on the smooth muscle?

Albuterol works by relaxing the smooth muscle of all the airways. It is a functional antagonist that relaxes the airway regardless of the cause of bronchoconstriction. Albuterol is a beta2-adrenergic agonist.

How does albuterol sulfate work in the trachea?

Mechanism Of Action. This increase of cyclic AMP leads to the activation of protein kinase A , which inhibits the phosphorylation of myosin and lowers intracellular ionic calcium concentrations, resulting in relaxation. Albuterol relaxes the smooth muscles of all airways, from the trachea to the terminal bronchioles.