What is methylergonovine maleate used for?

What is methylergonovine maleate used for?

Methylergonovine is used to prevent or treat bleeding from the uterus that can happen after childbirth or an abortion. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How do you administer Methergine?

1 mL, 0.2 mg, after delivery of the anterior shoulder, after delivery of the placenta, or during the puerperium. May be repeated as required, at intervals of 2-4 hours. 1 mL, 0.2 mg, administered slowly over a period of no less than 60 seconds (See WARNINGS.)

Can Methergine be given orally?

Methergine is available in tablets for oral ingestion containing 0.2 mg methylergonovine maleate.

How much methylergonovine maleate is in methergine tablets?

(methylergonovine maleate) is a semi-synthetic ergot alkaloid used for the prevention and control of postpartum hemorrhage. Methergine is available in sterile ampuls of 1 mL, containing 0.2 mg methylergonovine maleate for intramuscular or intravenous injection and in tablets for oral ingestion containing 0.2 mg methylergonovine maleate. Tablets

When to use methylergonovine maleate for uterine atony?

Intramuscular methylergonovine maleate (Methergine) is sometimes used to treat uterine atony but should not be used in women with hypertension because of vasoconstrictive properties (King & Brucker, 2011).

How long to take methylergonovine maleate after birth?

➣ Prevention and treatment of postpartum hemorrhage. Adults: 0.2 mg I.M.; repeat q 2 to 4 hours as needed to a total of five doses. In emergencies, 0.2 mg I.V. over 1 minute. After initial I.M. or I.V. dose, 0.2 mg P.O. q 6 to 8 hours for 2 to 7 days; decrease dosage if cramping occurs.

What is the plasma concentration of methylergonovine maleate?

Bioavailability studies conducted in fasting healthy female volunteers have shown that oral absorption of a 0.2 mg methylergonovine tablet was fairly rapid with a mean peak plasma concentration of 3243 ± 1308 pg/mL observed at 1.12 ± 0.82 hours.