Guidelines

What is Dichlorphenamide used for?

What is Dichlorphenamide used for?

What is dichlorphenamide? Dichlorphenamide is used to treat occasional paralysis (loss of movement) caused by high or low levels of potassium in your blood. Dichlorphenamide may also be used for purposes not listed in this medication guide.

What is the role of carbonic anhydrase in glaucoma?

Carbonic anhydrase inhibitors (CAIs) reduce eye pressure by decreasing the production of intraocular fluid. These are available as eye drops and as pills. If you need to use more than one type of eyedrop, you may need to take each medicine in a certain order as prescribed by your doctor.

What does a carbonic anhydrase inhibitor do?

In the eyes, carbonic anhydrase inhibitors reduce the production of aqueous humor by the epithelium of the ciliary body by reducing the production of bicarbonate ions and presumably reducing fluid flow.

How do carbonic anhydrase inhibitors act as diuretics?

Carbonic anhydrase inhibitors (acetazolamide) are weak diuretics, with the main site of action in the proximal tubular lumen and cell. Blockade of carbonic anhydrase leads to decreased bicarbonate and sodium reabsorption via the Na+/HCO3− cotransporter, resulting in reduced water reabsorption.

How is Diclofenamide used to treat glaucoma?

More… Diclofenamide is a sulfonamide that is benzene-1,3-disulfonamide in which the hydrogens at positions 4 and 5 are substituted by chlorine. An oral carbonic anhydrase inhibitor, it partially suppresses the secretion (inflow) of aqueous humor in the eye and so reduces intraocular pressure. It is used for the treatment of glaucoma.

What kind of drug is Diclofenamide used for?

Diclofenamide (or dichlorphenamide) is a sulfonamide and a carbonic anhydrase inhibitor of the meta -disulfamoylbenzene class. Diclofenamide was approved in the United States in 1958 as Daranide to treat glaucoma, Subsequently, it was found effective in cases of therapy-resistant epilepsy.

How is dichlorphenamide used in the eye?

An oral carbonic anhydrase inhibitor, it partially suppresses the secretion (inflow) of aqueous humor in the eye and so reduces intraocular pressure. It is used for the treatment of glaucoma. It has a role as an EC 4.2.1.1 (carbonic anhydrase) inhibitor, an antiglaucoma drug and an ophthalmology drug. It is a sulfonamide and a dichlorobenzene.

Which is an oral anhydrase inhibitor for glaucoma?

Dichlorphenamide is an oral carbonic anhydrase inhibitor indicated for adjunctive treatment of: chronic simple (open-angle) glaucoma, secondary glaucoma, and preoperatively in acute angle-closure glaucoma where delay of surgery is desired in order to lower intraocular pressure.