Guidelines

Is Zyprexa RElPREVV still available?

Is Zyprexa RElPREVV still available?

Because of this risk, ZYPREXA RElPREVV is available only through a restricted distribution program called ZYPREXA RElPREVV Patient Care Program and requires prescriber, healthcare facility, patient, and pharmacy enrollment.

How do you administer Zyprexa RElPREVV?

ZYPREXA RELPREVV should be administered by a healthcare professional every 2 to 4 weeks by deep intramuscular gluteal injection using a 19-gauge, 1.5-inch needle. Following insertion of the needle into the muscle, aspiration should be maintained for several seconds to ensure that no blood is drawn into the syringe.

Does olanzapine have a long-acting injectable?

Olanzapine long-acting injection (LAI) consists of a pamoate salt of olanzapine that is administered by deep intramuscular injection every 2–4 weeks. It has been available in 31countries for over 5 years for the treatment of schizophrenia in adults.

Can olanzapine be given by injection?

Olanzapine injection and olanzapine extended-release injection come as powders to be mixed with water and injected into a muscle by a healthcare provider. Olanzapine injection is usually given as needed for agitation.

Which is the correct IM formulation for olanzapine?

There are two IM formulations of olanzapine and these should not be confused: olanzapine (as pamoate monohydrate) depot injection (Zyprexa Relprevv) 210 mg, 300 mg or 405 mg* powder and sterile diluent for IM injection. *Olanzapine depot injection 405 mg is currently not available in Australia.

How often to take Zyprexa relprevv in elderly patients?

ZYPREXA IntraMuscular (10 mg/vial) is a short-acting formulation and should not be confused with ZYPREXA RELPREVV. (2.1) • and Company at 1Establish tolerability with oral olanzapine prior to initiating treatment. 1(2.1) • ZYPREXA RELPREVV doses above 405 mg every 4 weeks or 300 mg every 2 weeks have not been evaluated in clinical trials.

When to take olanzapine depot injection for relapse?

In a 6-month maintenance trial, most relapses occurred in the first 2 months of treatment with olanzapine depot injection in patients previously stabilised on oral olanzapine. 15 However, the doses used during this period may have been lower than the recommended starting doses in Table 1 .

What are the side effects of taking olanzapine?

In some cases extreme and associated with ketoacidosis or hyperosmolar coma or death, has been reported in patients taking olanzapine. Patients taking olanzapine should be monitored for symptoms of hyperglycemia and undergo fasting blood glucose testing at the beginning of, and periodically during, treatment. (5.6) • Hyperlipidemia: