Guidelines

How do you deal with sarcoma?

How do you deal with sarcoma?

Treatment of recurrent adult soft tissue sarcoma may include the following:

  1. Surgery (wide local excision) followed by radiation therapy.
  2. Surgery (amputation; rarely done).
  3. Surgery to remove cancer that has recurred in the lungs.
  4. Targeted therapy with a tyrosine kinase inhibitor (pazopanib).
  5. Chemotherapy.

What is extremity sarcoma?

Soft tissue sarcomas are a rare and heterogeneous group of tumors, representing less than 1% of all adult malignancies. Sixty percent of soft tissue sarcomas occur in the extremities, making this the commonest site. Other locations are the trunk (19%), the retroperitoneum (15%), and the head and neck (9%).

Is sarcoma chemo sensitive?

Soft tissue sarcomas represent a heterogenous group of neoplasms with differential sensitivity to chemotherapy. Their optimal management requires a multidisciplinary team approach.

What are the treatment options for soft tissue sarcoma?

Treatment of recurrent adult soft tissue sarcoma may include the following: Surgery (wide local excision) followed by radiation therapy. Surgery (amputation; rarely done). Surgery to remove cancer that has recurred in the lungs. Chemotherapy. A clinical trial of isolated limb perfusion.

How to tell if you have adult soft tissue sarcoma?

Key Points. Adult soft tissue sarcoma is a disease in which malignant (cancer) cells form in the soft tissues of the body. Having certain inherited disorders can increase the risk of adult soft tissue sarcoma. A sign of adult soft tissue sarcoma is a lump or swelling in soft tissue of the body.

Which is harder to diagnose low grade or high grade sarcoma?

High-grade tumors usually grow and spread more quickly than low-grade tumors. Because soft tissue sarcoma can be hard to diagnose, patients should ask to have tissue samples checked by a pathologist who has experience in diagnosing soft tissue sarcoma.

Is there a staging system for soft tissue sarcoma?

There is no standard staging system for soft tissue sarcoma of the head, neck, chest, or abdomen. Soft tissue sarcoma can recur (come back) after it has been treated. After adult soft tissue sarcoma has been diagnosed, tests are done to find out if cancer cells have spread within the soft tissue or to other parts of the body.