Which of the following is a nitroimidazole?

Nitroimidazole antibiotics Drugs of the 5-nitro variety include metronidazole, tinidazole, nimorazole, dimetridazole, pretomanid, ornidazole, megazol, and azanidazole. Drugs based on 2-nitromidazoles include benznidazole. Nitroimidazole antibiotics have been used to combat anaerobic bacterial and parasitic infections.

What are nitroimidazole used for?

Nitroimidazole antibiotics are used to treat parasitic infections, amoebiasis, bacterial vaginosis, gastrointestinal infections, skin infections, meningitis, lower respiratory infections, bacterial infections, diarrhea, and rosacea. They work by killing the bacteria causing the infection.

Is nitroimidazole the same as metronidazole?

Metronidazole. Metronidazole is a nitroimidazole antimicrobial with activity against protozoa and anaerobic bacteria but no activity against other bacteria. The mechanism of action involves the reduction of the nitro group on the antibiotic by nitroreductases produced by susceptible bacteria.

Is albendazole a nitroimidazole?

Albendazole is a synthetic nitroimidazole with a broad spectrum of antinematodal activity similar to that of mebendazole but also with anticestodal and some antiprotozoal action.

Which is the best 5-nitroimidazole for trichomonads and amebae?

The 5-nitroimidazoles are a group of drugs that have both antiprotozoal and antibacterial activity. Nitroimidazoles with activity against trichomonads and amebae include metronidazole, tinidazole, nimorazole, flunidazole, and ronidazole. Metronidazole and nimorazole are effective in treatment of giardiasis, whereas dimetridazole,…

How does nitroimidazoles work in the anaerobic environment?

The precise mode of action is unclear, but reduction in an anaerobic environment yields a compound that then binds to DNA, causing loss of the helical structure, strand breakage, and impairment of DNA function. Only susceptible organisms (bacteria and protozoa) appear to be capable of metabolizing the drug.

Is it safe to give nitroimidazoles to animals?

Extra-label use of nitroimidazoles is prohibited in food animals in the USA. Metronidazole has been used for many years in therapeutic management of trichomoniasis, giardiasis, and amebiasis. It is active against obligate anaerobic bacteria.

What are some examples of gender neutral pronouns?

Gender-neutral pronouns can refer to a group of people (the “plural they”) or a single person (the “singular they”). For example, “they went shopping” could indicate that a group of people went shopping together.