What are the signs and symptoms of hepatotoxicity?

What are the signs and symptoms of hepatotoxicity?


  • Yellowing of the skin and whites of the eyes (jaundice)
  • Itching.
  • Abdominal pain in the upper right portion of the abdomen.
  • Fatigue.
  • Loss of appetite.
  • Nausea and vomiting.
  • Rash.
  • Fever.

What are signs and symptoms of the drug-induced liver injury?

Typical symptoms of drug-induced hepatitis include:

  • loss of appetite,
  • nausea,
  • vomiting,
  • fever,
  • weakness,
  • tiredness, and.
  • abdominal pain.

How is drug-induced hepatotoxicity treated?

Treatment of drug and herbal-induced liver injury consists of rapid drug discontinuation and supportive care targeted to alleviate unwanted symptoms. Adverse drug reactions are an important cause of liver injury that may require discontinuation of the offending agent, hospitalization, or even liver transplantation.

What are the symptoms of drug hepatotoxicity?

Symptoms of drug hepatotoxicity usually subside once the drug is withdrawn. They also depend on the type of liver injury and the degree of damage to the liver. Symptoms of hepatotoxicity may include the following: Extreme exhaustion and fatigue. Fever.

How do you know if you have drug induced liver disease?

Since these patients typically experience no symptoms or signs, the elevations of liver enzymes usually are discovered when blood tests are performed as a part of an annual physical examination, as pre-operative screening, or as a part of periodic monitoring for drug toxicity.

Can a drug interaction lead to hepatotoxicity?

Drug Interactions that can lead to Hepatotoxicity- It is not only hepatotoxic drugs that can cause hepatotoxicity, but some drugs when combined may react and in the end also lead to hepatotoxicity. These are only a few examples of drug combinations that can lead to liver toxicity:

Is there a cure for drug induced hepatotoxicity?

Regular blood tests monitoring, as of now, has no apparent proof that can avoid significant drug-induced hepatotoxicity. A lot of these occurrences are irregular and arrive fast. Management of hepatotoxicity is dependent upon the etymology of the disease, the scale of liver impairment, and the age and overall physical condition of the patient.