How fast can you IV push ondansetron?

The recommended intravenous dose of ondansetron is 8 mg administered as a slow injection (in not less than 30 seconds) or as an infusion over 15 minutes immediately before treatment, followed by treatment with dosage forms other than intravenous.

How do you give ondansetron IV?

For intravenous infusion (Zofran ®), give continuously or intermittently in Glucose 5% or Glucose 5% with Potassium chloride 0.3% or Sodium chloride 0.9% or Sodium chloride 0.9% with Potassium chloride 0.3% or Mannitol 10% or Ringers solution; for intermittent infusion, dilute the required dose in 50–100 mL of infusion …

How fast should Zofran 8 mg IV push be administered?

Emetogenic chemotherapy and radiotherapy: The recommended intravenous or intramuscular dose of Zofran is 8 mg administered as a slow injection in not less than 30 seconds immediately before treatment.

What happens if you push IV Zofran too fast?

Do not give this medication any faster than recommended or take more than the recommended dose because this may increase the chance of serious side effects such as blurred vision or slowed/irregular heartbeat.

Why is IV ondansetron given slowly?

Perhaps slow administration of ondansetron as recommended over 2-5 min would decrease the incidence of potentially life-threatening adverse effects associated with ondansetron.

Why is ondansetron given slowly?

Does Zofran need to be pushed slow?

How do you administer IV push?

Connect your medication syringe to the hub of your IV line using a “push and twist” motion. Disengage clamps, Slowly push the medication syringe to the speed noted in your medication orders. Once your medication syringe is empty, remove the syringe from the hub of your IV line. WASH HANDS.

Can ondansetron give you a high?

No, Ondanestron does not make you feel high, it is a drug that can stop you feeling sick and is often given to people who abuse substances. Ondansetron is a drug that was developed in 1984 by GlaxoSmithKline in London. The drug is usually used to treat vomiting and nausea, particularly chemotherapy induced nausea.

How fast does ondansetron work?

Ondansetron works in the stomach to block the signals to the brain that cause nausea and vomiting. The standard tablets that are swallowed will start to work within half an hour to 2 hours.

Can You overdose on ondansetron?

If you overdose on Zofran, call 911 or your local Poison Control Center at 1-800- 222-1222. An overdose of Zofran (ondansetron) can greatly increase the risk of serious side effects such as blurred vision or even temporary blindness, severe constipation, feeling light-headed, or passing out.

What is the mechanism of ondansetron?

Ondansetron is a carbazole derivative with antiemetic activity. As a selective serotonin receptor antagonist, ondansetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. (NCI04) Ondansetron is a well tolerated drug with few side effects.